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Hydrogels for Osteochondral
Tissue Engineering
Journal of Biomedical

(March 2020)
Anti-Wrinkle Activity
& Transdermal Delivery
of GHK Peptide
Journal of Peptide Science
(March 2020)
Pulsed Glow Discharge
to GHK-Cu Determination
International Journal
of Mass Spectrometry

(March 2020)
Protective Effects of GHK-Cu
in Pulmonary Fibrosis
Life Sciences
(January 2020)
Anti-Wrinkle Benefits
of GHK-Cu Stimulating
Skin Basement Membrane
International Journal of Molecular Sciences
(January 2020)
Structural Analysis
Molecular Dynamics of
Skin Protective
TriPeptide GHK
Journal of Molecular Structure
(January 2020)
In Vitro / In Vivo Studies
pH-sensitive GHK-Cu in
Superabsorbent Polymer
GHK Enhances
Stem Cells Osteogenesis
Acta Biomaterialia
Antibacterial GHK-Cu
Nanoparticles for
Wound Healing
Particle & Particle (2019)
Effect of GHK-Cu
on Stem Cells and
Relevant Genes
OBM Geriatrics
GHK Alleviates
Neuronal Apoptosis Due
to Brain Hemorrhage
Frontiers in Neuroscience
Endogenous Antioxidant
International Journal of Pathophysiology and Pharmacology (2018)
Regenerative and
Protective Actions of
GHK-Cu Peptide
International Journal of
Molecular Sciences
Skin Regenerative and
Anti-Cancer Actions
of Copper Peptides
GHK-Cu Accelerates
Scald Wound Healing
Promoting Angiogenesis
Wound Repair and

GHK Peptide Inhibits
Pulmonary Fibrosis
by Suppressing TGF-β1
Frontiers in Pharmacology
Skin Cancer Therapy
with Copper Peptides
The Effect of Human
Peptide GHK Relevant to
Nervous System Function
and Cognitive Decline
Brain Sciences (2017)
Effects of Tripeptide
GHK in Pain-Induced
Aggressive Behavior
Bulletin of Experimental
Biology & Medicine
GHK-Cu Elicits
In Vitro Alterations
in Extracellular Matrix
Am Journal of Respiratory
and Critical Care Medicine

Selected Biomarkers &
Copper Compounds
Scientific Reports

GHK-Cu on Collagen,
Elastin, and Facial Wrinkles
Journal of Aging Science
Tri-Peptide GHK-Cu
and Acute Lung Injury

Effect of GHK Peptide
on Pain Sensitivity
Experimental Pharmacology

New Data of the
Cosmeceutical and
TriPeptide GHK
SOFW Journal
GHK Peptide as a
Natural Modulator of
Multiple Cellular Pathways
in Skin Regeneration
BioMed Research (2015)
Resetting Skin Genome
Back to Health
Naturally with GHK
Textbook of Aging Skin
GHK-Cu May Prevent
Oxidative Stress in Skin
by Regulating Copper and
Modifying Expression of
Numerous Antioxidant Genes Cosmetics (2015)
GHK Increases
TGF-β1 in
Human Fibroblasts

Acta Poloniae

The Human Skin Remodeling Peptide Induces Anti-Cancer
Expression and DNA Repair Analytical Oncology
Resetting the
Human Genome to Health
BioMed Research
Enhanced Tropic Factor Secretion of Mesenchymal
Stem Cells with GHK
Acta Biomater
Anxiolytic (Anti-Anxiety)
Effects of GHK Peptide
Bulletin of Experimental
Biology & Medicine
Lung Destruction and
its Reversal by GHK
Genome Medicine
TriPeptide GHK Induces
Programmed Cell Death
of Neuroblastoma
Journal of Biotechnology
Stem Cell
Recovering Effect
of GHK in Skin
Peptide Science
Skin Penetration of
Copper Tripeptide in Vitro
Journal of International
Inflammation Research
Possible Therapeutics
for Colorectal Cancer
Journal of Clinical and
Experimental Metastasis
Methods of Controlling
Differentiation and
Proliferation of Stem Cells
Effects of
Copper Tripeptide
on Irradiated Fibroblasts
American Medical Association
Avoid Buying Fake Copper Peptides Dangerous

What Is Eczema?

Unknown-Artist---BlushYou woke up this morning with red, scaling, itchy and bumpy skin, wondering if there is a safe, effective treatment for dryness and sensitivity. If this statement describes you, read on.

Affecting around three percent of adults and as much as 20 percent of children, eczema-afflicted skin often develops an itchy rash as the immune system overreacts in response to irritants, detergents, cold temperatures, prolonged wetness as well as many cosmetic products. Even Kate Middleton admits that she once suffered the childhood embarrassment of recurring eczema flare-ups.

What happens when necessary moisture leaves the skin and pollen, dust mites, and bacteria enter? A frequent symptom is itchy skin; scratching can lead to local darkening and hardening of the skin and possibly pockets of oozing or swelling. The natural instinct is to find a remedy that will gently repair damaged skin and restore its balance.

Avoid Irritants!


If you have eczema, the primary concern should be reducing contact with irritants.

Surprisingly, many cosmetic products that are supposed to improve your skin contain artificial dyes, perfumes and detergents that can make eczema even worse. These ingredients, which may lend a pleasant odor and texture to products, actually cause damage to sensitive skin.

Another aggravating factor is frequent washing with hot water and alkaline soaps. Harsh alkaline soaps shift the acid balance of the skin, delay skin cell turnover and reduce beneficial bacteria that keep bad germs away. Feel free to bathe skin daily, but remember to use mild soap and a product to seal in moisture afterwards.

Many so-called "anti-aging" creams contain detergents that cause swelling of the skin’s proteins, creating an immediate illusion of wrinkle reduction. But this swelling can further weaken the skin’s protective barrier, making eczema even worse.

Exotic plants and new “miracle” ingredients that are foreign to your skin’s biology can further exacerbate eczema symptoms. Once the cause of irritation is found, you may need to find a product that can help with symptoms until the sensitivity reaction goes away.

"What could the offending substance be?", you are often left to wonder. A preservative, a food allergy, a fragrance, a new soap? It could be any of these things, really. Only by eliminating suspected triggers one at a time will you be able to find the cause of that aggravating itch and formulate your unique path to recovery.

Will Moisturizers Help?

It is important to hold moisture inside the skin, but moisturizers don't always help. Confused? Don't be. Moisturizers and emollients provide temporary relief by softening a dry and cracked upper skin layer, thereby preventing further cracking. However, they need to be constantly re-applied, and it would be better to address the cause of the problem.

Many moisturizers wet the skin too much, loosening protective keratinous scales and creating new entrance for irritants. Petrolatum can slow down skin cell turnover and delay barrier restoration.

Some moisturizers, including many trendy and popular creams, commonly contain artificial perfumes which aggravate the allergic response seen in eczema breakouts, especially if the percentage of fragrance is over one percent.

A Unique Approach


Just as many factors can exacerbate eczema, there are many methods that can help your skin to heal.

Assisting your skin’s natural defenses is the best way of dealing with many skin conditions, especially the compromised skin barrier and sensitivity symptoms of eczema.

Truly mild soaps provide gentle cleansing that very inflamed skin needs. However, many so called "mild" soaps possess a high alkalinity of pH 9.5-11. These alkaline cleansers deplete the natural acid that protects skin while also extracting protective lipids (fats).

Use mild facial cleansers with a pH from 5.5 to 7 that soothe damaged skin by restoring its acid balance. A slightly acidic pH of 5.5 is healthy for the outer layer of skin.

There is no better way to deeply moisturize eczema skin than pure natural healing oils such as squalane (a natural component of skin’s sebum) and hypoallergenic and odorless Emu oil. Eczema skin requires products that leave skin refreshed, repaired, and soft. Natural oils have skin-calming qualities that condition dry skin without filler ingredients or artificial fragrances. Squalane can be cold-pressed from olives; the resulting clear liquid safely softens the skin and protects it from environmental assaults while possessing the pleasant tendency to sink in quickly, leaving no residue. Emu oil, with high amounts of nourishing omega fatty acids, also has excellent penetrative ability and effectively reduces inflammation. Application of these non-comedogenic oils is an important step in the care of your eczema as they guard against microorganisms and keep water in the skin.

Emu Oil, derived from the flightless bird of the same name, is an ancient healing remedy used by Australian indigenous people to treat wounds, insect bites and inflamed sores. Natural oils provide a coating that moisturizes irritated skin while being very gentle as they are agreeable with your skin's natural chemistry. Apply healing oils as a thin layer after taking a bath or a shower to trap moisture. Use them any time of the day when your skin feels dry. It is guaranteed that as you feel these incredibly soft oils soak into your epidermis, you'll wonder how you ever got by without them. In addition to healing oil, apply a thin coat of copper-peptides based product. This easy routine, which uses only safe and bio-compatible ingredients, will save your skin from the discomfort of unattractive rashes and swelling and soon restore your skin's health and integrity.

Copper peptides supply nutritional copper to the skin which is then used by over a dozen important skin enzymes. Using your body's natural healing factors, they efficiently improve skin’s barrier, reduce inflammation and speed up cell turnover.

Copper peptides improved the skin barrier in four independent studies by world renowned dermatologists at leading universities. In addition, research indicates that the copper peptide GHK-Cu discovered by Dr. Pickart in 1973 may help by regulating your skin’s genes. The Cleveland Clinic refers to copper peptides as "the most effective skin regeneration product" and explains that they "increase the benefits of the body's natural tissue-building processes". Much research has been done on this tiny molecule with differing uses pinpointed, including the visible improvement of dry, broken skin.

GHK was also shown to regulate genes involved in the ubiquitin-proteasome system – which is the cell’s waste disposal station, designed to clean the cell from damaged or altered proteins. There is no better time to benefit from this burgeoning technology than the present. Clinically tested copper peptides deliver powerful results without unpleasant side effects or time-consuming procedures.

In addition to copper peptides, lesser-known tin peptides may help to improve skin keratinization and preserve skin's moisture. Even though they lack wound healing properties of copper peptides, they work well at strengthening the protective skin barrier while preventing irritation and cracking.


If you like what you've read so far but need more information about safe, innovative skin care, contact Dr. Pickart during business hours.

revised 5/31/18

The information provided on this website is for educational purposes only.
Any suggestions mentioned are not for the treatment or prevention of any skin disease or condition.
If you have a special skin concern, please consult a physician or dermatologist first.


Questions or Advice?

Ask Dr. Loren Pickart:

Call us at 1-800-405-1912 Monday through Friday (8 am to 6 pm) PST